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EXPERIMENTAL STUDY ON THE EFFECT OF X-RAY IRRADIATION ON THE RAT MANDIBLE DEVELOPMENT

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Abstract

îÊíº´Â ìõããÛÜà©¿¡´Ù ÒýåÖÀÇ X-àÊÀ» ðÎÞÒÇÏ°í ±× ç¯úÂÀÌ í¨ÛÜà©ÀÇ ù»äÉÍéÛ¡ëÀ¿¡ ¹ÌÄ¡´Â
¹Ù¸¦ κóÌÇÏ¿´´Ù.
X-àÊðÎÞÒÛ°ÛöÀº ìõãã 7¨öìí° µÇ´Â ³¯¿¡ 100rads, 200rads, 300rads ¹× 400rads Ù½ô÷ í­
ÏàÊÇÝ»¿¡ ðÎÞÒÇÑ ÈÄ 18¨öìí µÇ´Â ¶§¿Í ßæý­ 1ñÎ 2ñÎ ¹× 3ñÎÊà ÞøëÀÇÑ í¨ÛÜà©¿¡¼­ κóÌµÈ Ì¿
Íý´Â ´ÙÀ½°ú °°´Ù.
1. ìéÚõîÜÀ¸·Î àÊåÖÀÌ ñòÊ¥ÇÔ¿¡ µû¶ó ÍéòõÀÇ Û¡ëÀßÓÀÌ ÝÕåÐÇÏ¿´´Ù.
2. 18¨öìí¿¡ î×õóµÈ ÌÑéç¿¡¼­´Â 100rads ¹× 200rads ðÎÞÒÏØ¿¡¼­´Â ÍéòõÀÇ Û¡ëÀ î¡äô°¡ ä¤
ÇÏÁö ¾Ê¾ÒÀ¸³ª 300rads ¹× 400rads ðÎÞÒÏØ¿¡¼­´Â ÍéÕÚÀÇ ÝÕЮöÎÇÑ ÛÕÖªÀÌ ä¤ÇÏ°í Íéá¬øàÀÇ
ܨàõµÈ °Íµµ ¸¹ÀÌ ³ªÅ¸³µ´Ù.
3. ßæý­ 1ñÎ ÌèΦµÈ ÌÑéç¿¡´Â Íéá¬øàÀÇ Ü¨àõ°ú ÷òÍéá¬øàÀÇ õóúÞÀÌ úéîÊÇÏ¿´´Ù.
4. ßæý­ 2ñÎ ¹× 3ñÎ ÌèΦµÈ ÌÑéç¿¡¼­´Â ÍéÀÇ ËÇðãúÞßÚÀÌ úéîÊÇÏ¿´°í ܨàõµÈ úìηµµ κóÌ
µÇ¾ú´Ù.

The author observed the effect of x-ray irradiation on the development of the
mandible in the fetuses and growing albino rats. The fetuses were irradiated on the 7¨ö
th day of gestation, 100, 200, 300, and 400 rads of x-ray respectively. The experimental
animals were sacrificed on the 18¨öth day of gestation, and first week, second week and
third week after parturition.
The results were as follows ;
1. The mandible of the 18¨öth day fetuses showed irregular bone trabeoulae,
osteoclasts and osteocyte degeneration on the 300 and 400 rads x-ray irradiated fetuses.
2. In the mandible of the first week rats, there was marked osteocyte degeneration
and a lot of osteoclast.
3. In the mandible of the 2nd and 3rd week rats bone remodeling was evident. The
3rd week rats also showed alteration of blood vessel wall.

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